Georges Thienpont, of the great wine-making family in Bordeaux, purchased Château Puygueraud, located in the Cotes de Francs wine appellation, in 1946. The vineyards had been devastated by the two World Wars, and so the land was initially used to grow cereal and farm cattle.
In 1979, he started to replant the vineyards, and in 1983 he was joined by his son Nicolas Thienpont to help produce the first vintage.

The vineyard comprises 70% Merlot, 25% Cabernet Franc and 5% Malbec grapes. The soil consists of clay and limestone, with chalky subsoil. Vines are planted with a vine density of 4,500 vines per hectare.

In 2013, Château Puygueraud launched Puygueraud Blanc, a Bordeaux AOC white wine. The white grapes are composed of 55% Sauvignon Gris and 45% Sauvignon Blanc, representing the highest percentage of Sauvignon Gris used in Bordeaux. Château Puygueraud also produces Cuvée George, as a tribute to George Thienpont, which is a blend of Malbec and Cabernet.

Nowadays, Nicolas manages not only Château Puygueraud, but also several well-known St Emilion estates such as Berliquet and Larcis Ducasse.